Repurposing sertraline sensitizes non–small cell lung cancer cells to erlotinib by inducing autophagy

Lung cancer patients treated with tyrosine kinase inhibitors (TKIs) often develop resistance. More effective and safe therapeutic agents are urgently needed to overcome TKI resistance. Here, we propose a medical genetics–based approach to identify indications for over 1,000 US Food and Drug Administ...

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Detalles Bibliográficos
Autores principales: Jiang, Xingwu, Lu, Weiqiang, Shen, Xiaoyang, Wang, Quan, Lv, Jing, Liu, Mingyao, Cheng, Feixiong, Zhao, Zhongming, Pang, Xiufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124398/
https://www.ncbi.nlm.nih.gov/pubmed/29875309
http://dx.doi.org/10.1172/jci.insight.98921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124398/
https://www.ncbi.nlm.nih.gov/pubmed/29875309
http://dx.doi.org/10.1172/jci.insight.98921

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