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Methyl jasmonate enhances the radiation sensitivity of esophageal carcinoma cells by inhibiting the 11-ketoprostaglandin reductase activity of AKR1C3

PURPOSE: In our previous study, we found that AKR1C3 was a radioresistance gene in KY170R cells. Downregulating the expression of AKR1C3 could enhance the radiosensitivity of esophageal carcinoma cells. In this study, we investigated whether methyl jasmonate (MeJ), an inhibitor of Aldo-keto reductas...

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Detalles Bibliográficos
Autores principales: Li, Xiaoying, Hong, Xin, Gao, Xianshu, Gu, Xiaobin, Xiong, Wei, Zhao, Jing, Yu, Hongliang, Cui, Ming, Xie, Mu, Bai, Yun, Sun, Shaoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124458/
https://www.ncbi.nlm.nih.gov/pubmed/30214307
http://dx.doi.org/10.2147/CMAR.S166942