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Gomisin A Suppresses Colorectal Lung Metastasis by Inducing AMPK/p38-Mediated Apoptosis and Decreasing Metastatic Abilities of Colorectal Cancer Cells

Gomisin A (G.A) is a dietary lignan compound from Schisandra chinensis. In this study, the effect of G.A on the proliferation and metastasis of colorectal cancer (CRC) cells was investigated using several CRC cell lines and a lung metastasis mouse model. Both oral and intraperitoneal administration...

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Detalles Bibliográficos
Autores principales: Kee, Ji-Ye, Han, Yo-Han, Mun, Jeong-Geon, Park, Seong-Hwan, Jeon, Hee D., Hong, Seung-Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124511/
https://www.ncbi.nlm.nih.gov/pubmed/30210348
http://dx.doi.org/10.3389/fphar.2018.00986