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Three-dimensional induction of dorsal, intermediate and ventral spinal cord tissues from human pluripotent stem cells

The spinal cord contains more than 20 distinct subclasses of neurons that form well-organized neural circuits capable of sensing the environment and generating motor behavior. Although recent studies have described the efficient in vitro generation of spinal motor neurons, the induction of the spina...

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Detalles Bibliográficos
Autores principales: Ogura, Takenori, Sakaguchi, Hideya, Miyamoto, Susumu, Takahashi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124545/
https://www.ncbi.nlm.nih.gov/pubmed/30061169
http://dx.doi.org/10.1242/dev.162214