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Human trophoblasts are primarily distinguished from somatic cells by differences in the pattern rather than the degree of global CpG methylation

The placenta is a fetal exchange organ connecting mother and baby that facilitates fetal growth in utero. DNA methylation is thought to impact placental development and function. Global DNA methylation studies using human placental lysates suggest that the placenta is uniquely hypomethylated compare...

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Detalles Bibliográficos
Autores principales: Gamage, Teena K. J. B., Schierding, William, Tsai, Peter, Ludgate, Jackie L., Chamley, Lawrence W., Weeks, Robert J., Macaulay, Erin C., James, Joanna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124577/
https://www.ncbi.nlm.nih.gov/pubmed/30026266
http://dx.doi.org/10.1242/bio.034884