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Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: analysis using transgenic and mutant zebrafish

Hemogen is a vertebrate transcription factor that performs important functions in erythropoiesis and testicular development and may contribute to neoplasia. Here we identify zebrafish Hemogen and show that it is considerably smaller (∼22 kDa) than its human ortholog (∼55 kDa), a striking difference...

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Detalles Bibliográficos
Autores principales: Peters, Michael J., Parker, Sandra K., Grim, Jeffrey, Allard, Corey A. H., Levin, Jonah, Detrich, H. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124579/
https://www.ncbi.nlm.nih.gov/pubmed/30097520
http://dx.doi.org/10.1242/bio.035576