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Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression

BACKGROUND: Summary data furnishing a two-sample Mendelian randomization (MR) study are often visualized with the aid of a scatter plot, in which single-nucleotide polymorphism (SNP)–outcome associations are plotted against the SNP–exposure associations to provide an immediate picture of the causal-...

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Detalles Bibliográficos
Autores principales: Bowden, Jack, Spiller, Wesley, Del Greco M, Fabiola, Sheehan, Nuala, Thompson, John, Minelli, Cosetta, Davey Smith, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124632/
https://www.ncbi.nlm.nih.gov/pubmed/29961852
http://dx.doi.org/10.1093/ije/dyy101