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Mendelian randomization with Egger pleiotropy correction and weakly informative Bayesian priors
BACKGROUND: The MR-Egger (MRE) estimator has been proposed to correct for directional pleiotropic effects of genetic instruments in an instrumental variable (IV) analysis. The power of this method is considerably lower than that of conventional estimators, limiting its applicability. Here we propose...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124638/ https://www.ncbi.nlm.nih.gov/pubmed/29253155 http://dx.doi.org/10.1093/ije/dyx254 |