Differential Regulation of Human Bone Marrow Mesenchymal Stromal Cell Chondrogenesis by Hypoxia Inducible Factor‐1α Hydroxylase Inhibitors

The transcriptional profile induced by hypoxia plays important roles in the chondrogenic differentiation of marrow stromal/stem cells (MSC) and is mediated by the hypoxia inducible factor (HIF) complex. However, various compounds can also stabilize HIF's oxygen‐responsive element, HIF‐1α, at no...

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Detalles Bibliográficos
Autores principales: Taheem, Dheraj K., Foyt, Daniel A., Loaiza, Sandra, Ferreira, Silvia A., Ilic, Dusko, Auner, Holger W., Grigoriadis, Agamemnon E., Jell, Gavin, Gentleman, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124654/
https://www.ncbi.nlm.nih.gov/pubmed/29726060
http://dx.doi.org/10.1002/stem.2844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124654/
https://www.ncbi.nlm.nih.gov/pubmed/29726060
http://dx.doi.org/10.1002/stem.2844

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