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Differential Regulation of Human Bone Marrow Mesenchymal Stromal Cell Chondrogenesis by Hypoxia Inducible Factor‐1α Hydroxylase Inhibitors
The transcriptional profile induced by hypoxia plays important roles in the chondrogenic differentiation of marrow stromal/stem cells (MSC) and is mediated by the hypoxia inducible factor (HIF) complex. However, various compounds can also stabilize HIF's oxygen‐responsive element, HIF‐1α, at no...
Autores principales: | Taheem, Dheraj K., Foyt, Daniel A., Loaiza, Sandra, Ferreira, Silvia A., Ilic, Dusko, Auner, Holger W., Grigoriadis, Agamemnon E., Jell, Gavin, Gentleman, Eileen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124654/ https://www.ncbi.nlm.nih.gov/pubmed/29726060 http://dx.doi.org/10.1002/stem.2844 |
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