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Validation of diffusion tensor imaging measures of nigrostriatal neurons in macaques

OBJECTIVE: Interpretation of diffusion MRI in the living brain requires validation against gold standard histological measures. We compared diffusion values of the nigrostriatal tract to PET and histological results in non-human primates (NHPs) with varying degrees of unilateral nigrostriatal injury...

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Detalles Bibliográficos
Autores principales: Shimony, Joshua S., Rutlin, Jerrel, Karimi, Morvarid, Tian, Linlin, Snyder, Abraham Z., Loftin, Susan K., Norris, Scott A., Perlmutter, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124722/
https://www.ncbi.nlm.nih.gov/pubmed/30183721
http://dx.doi.org/10.1371/journal.pone.0202201