Cargando…

Probing key elements of teixobactin–lipid II interactions in membranes

Teixobactin (Txb) is a recently discovered antibiotic against Gram-positive bacteria that induces no detectable resistance. The bactericidal mechanism is believed to be the inhibition of cell wall biosynthesis by Txb binding to lipid II and lipid III. Txb binding specificity likely arises from targe...

Descripción completa

Detalles Bibliográficos
Autores principales: Wen, Po-Chao, Vanegas, Juan M., Rempe, Susan B., Tajkhorshid, Emad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124899/
https://www.ncbi.nlm.nih.gov/pubmed/30210775
http://dx.doi.org/10.1039/c8sc02616e