Bifunctional iminophosphorane catalysed enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles

The first enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles, enabled by a bifunctional iminophosphorane (BIMP) organocatalyst, is described. The iminophosphorane moiety of the catalyst provides the required basicity to deprotonate the thiol nucleophile while the chira...

Descripción completa

Detalles Bibliográficos
Autores principales: Formica, Michele, Sorin, Geoffroy, Farley, Alistair J. M., Díaz, Jesús, Paton, Robert S., Dixon, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124915/
https://www.ncbi.nlm.nih.gov/pubmed/30210771
http://dx.doi.org/10.1039/c8sc01804a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124915/
https://www.ncbi.nlm.nih.gov/pubmed/30210771
http://dx.doi.org/10.1039/c8sc01804a

Ejemplares similares