Stage-dependent remodeling of projections to motor cortex in ALS mouse model revealed by a new variant retrograde-AAV9

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive degeneration of motoneurons in the primary motor cortex (pMO) and in spinal cord. However, the pathogenic process involves multiple subnetworks in the brain and functional MRI studies demonstrate an increase in functional connec...

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Detalles Bibliográficos
Autores principales: Commisso, Barbara, Ding, Lingjun, Varadi, Karl, Gorges, Martin, Bayer, David, Boeckers, Tobias M, Ludolph, Albert C, Kassubek, Jan, Müller, Oliver J, Roselli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125125/
https://www.ncbi.nlm.nih.gov/pubmed/30136928
http://dx.doi.org/10.7554/eLife.36892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125125/
https://www.ncbi.nlm.nih.gov/pubmed/30136928
http://dx.doi.org/10.7554/eLife.36892

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