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Loss of ATF3 exacerbates liver damage through the activation of mTOR/p70S6K/ HIF-1α signaling pathway in liver inflammatory injury

Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays important roles in regulating immune and metabolic homeostasis. Activation of the mechanistic target of rapamycin (mTOR) and hypoxia-inducible factor (HIF) transcription factors are crucial for the regulatio...

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Detalles Bibliográficos
Autores principales: Zhu, Qiang, Wang, Han, Jiang, Bin, Ni, Xuhao, Jiang, Longfeng, Li, Changyong, Wang, Xuehao, Zhang, Feng, Ke, Bibo, Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125320/
https://www.ncbi.nlm.nih.gov/pubmed/30185770
http://dx.doi.org/10.1038/s41419-018-0894-1