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Loss of ATF3 exacerbates liver damage through the activation of mTOR/p70S6K/ HIF-1α signaling pathway in liver inflammatory injury
Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays important roles in regulating immune and metabolic homeostasis. Activation of the mechanistic target of rapamycin (mTOR) and hypoxia-inducible factor (HIF) transcription factors are crucial for the regulatio...
Autores principales: | Zhu, Qiang, Wang, Han, Jiang, Bin, Ni, Xuhao, Jiang, Longfeng, Li, Changyong, Wang, Xuehao, Zhang, Feng, Ke, Bibo, Lu, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125320/ https://www.ncbi.nlm.nih.gov/pubmed/30185770 http://dx.doi.org/10.1038/s41419-018-0894-1 |
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