Cargando…

Histamine causes endothelial barrier disruption via Ca(2+)-mediated RhoA activation and tension at adherens junctions

During inflammation, the disruption of the endothelial barrier leads to increased microvascular permeability. Whether tension along cell junctions contributes to histamine-induced endothelial barrier disruption remains unknown. Rapid Ca(2+) influx induced by both histamine and thrombin was accompani...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kugelmann, Daniela, Rotkopf, Lukas Thomas, Radeva, Mariya Yosifova, Garcia-Ponce, Alexander, Walter, Elias, Waschke, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125323/ https://www.ncbi.nlm.nih.gov/pubmed/30185878 http://dx.doi.org/10.1038/s41598-018-31408-3

Ejemplares similares

Lack of adducin impairs the stability of endothelial adherens and tight junctions and may be required for cAMP-Rac1-mediated endothelial barrier stabilization
por: Moztarzadeh, Sina, et al.
Publicado: (2022)

Distinct functions for Rho1 in maintaining adherens junctions and apical tension in remodeling epithelia
por: Warner, Stephen J., et al.
Publicado: (2009)

Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
por: Zhang, Jason Z., et al.
Publicado: (2020)

Adducin Is Involved in Endothelial Barrier Stabilization
por: Kugelmann, Daniela, et al.
Publicado: (2015)

The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation
por: Song, Soonhwa, et al.
Publicado: (2022)

Cdc42 antagonizes Rho1 activity at adherens junctions to limit epithelial cell apical tension
por: Warner, Stephen J., et al.
Publicado: (2009)

PKA Compartmentalization via AKAP220 and AKAP12 Contributes to Endothelial Barrier Regulation
por: Radeva, Mariya Y., et al.
Publicado: (2014)

Tension across adherens junctions: when less is more
por: Kruse, Kevin, et al.
Publicado: (2015)

Involvement of Histamine and RhoA/ROCK in Penicillin Immediate Hypersensitivity Reactions
por: Han, Jiayin, et al.
Publicado: (2016)

CCL2 Disrupts the Adherens Junction: Implications for Neuroinflammation
por: Roberts, Toni K., et al.
Publicado: (2012)

RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock
por: Mikelis, Constantinos M., et al.
Publicado: (2015)

Cytoskeletal anchorage of different Dsg3 pools revealed by combination of hybrid STED/SMFS-AFM
por: Fuchs, Michael, et al.
Publicado: (2023)

Bistable front dynamics in a contractile medium: Travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions
por: Priya, Rashmi, et al.
Publicado: (2017)

ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens
por: Priya, Rashmi, et al.
Publicado: (2017)

Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension
por: Lee, Natalie K., et al.
Publicado: (2016)

Formin' adherens junctions
por: Wells, William A.
Publicado: (2004)

Virtual adherens junctions
por: Wells, William A.
Publicado: (2006)

Formation of adherens junctions leads to the emergence of a tissue-level tension in epithelial monolayers
por: Harris, Andrew R., et al.
Publicado: (2014)

Excess centrosomes disrupt vascular lumenization and endothelial cell adherens junctions
por: Buglak, Danielle B., et al.
Publicado: (2020)

Spatially restricted activation of RhoA at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis
por: Terry, Stephen J., et al.
Publicado: (2011)

p115RhoGEF activates RhoA to support tight junction maintenance and remodeling
por: Chumki, Shahana A., et al.
Publicado: (2022)

Molecular heterogeneity of adherens junctions
Publicado: (1985)

Adherens junctions remain dynamic
por: Falk, Matthias M
Publicado: (2010)

ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation
por: Tornavaca, Olga, et al.
Publicado: (2015)

Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF
por: Scott, David W., et al.
Publicado: (2016)

Pemphigus Foliaceus Autoantibodies Induce Redistribution Primarily of Extradesmosomal Desmoglein 1 in the Cell Membrane
por: Hiermaier, Matthias, et al.
Publicado: (2022)

The RhoGAP protein Deleted in Liver Cancer 3 (DLC3) is essential for adherens junctions integrity
por: Holeiter, G, et al.
Publicado: (2012)

MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells
por: Breznau, Elaina B., et al.
Publicado: (2015)

Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins
por: Schmidt, Anja, et al.
Publicado: (2023)

Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins
por: Peifer, Mark, et al.
Publicado: (2023)

Switching adherens junctions to seal wounds
por: Leslie, Mitch
Publicado: (2011)

Building up actin at adherens junctions
por: Short, Ben
Publicado: (2012)

Adherens Junctions: Guardians of Cortical Development
por: Veeraval, Lenin, et al.
Publicado: (2020)

Predominant Distribution of the RNAi Machinery at Apical Adherens Junctions in Colonic Epithelia Is Disrupted in Cancer
por: Nair-Menon, Joyce, et al.
Publicado: (2020)

Desmosome-anchored intermediate filaments facilitate tension-sensitive RhoA signaling for epithelial homeostasis
por: Nanavati, Bageshri Naimish, et al.
Publicado: (2023)

RhoA improves cryopreservation of rooster sperm through the Rho/RhoA-associated kinase/cofilin pathway
por: Heng, Nuo, et al.
Publicado: (2022)

Rho1 regulates adherens junction remodeling by promoting recycling endosome formation through activation of myosin II
por: Yashiro, Hanako, et al.
Publicado: (2014)

RhoA is down-regulated at cell–cell contacts via p190RhoGAP-B in response to tensional homeostasis
por: Ponik, Suzanne M., et al.
Publicado: (2013)

Rotavirus-Induced Early Activation of the RhoA/ROCK/MLC Signaling Pathway Mediates the Disruption of Tight Junctions in Polarized MDCK Cells
por: Soliman, Mahmoud, et al.
Publicado: (2018)

VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module
por: Oldenburg, Joppe, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_d77evg6cnc9i05d8n7ahtgv3nn