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Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells

The fibrotic reaction is a characteristic feature of human pancreatic ductal adenocarcinoma (PDAC) tumors. It is associated with activation and proliferation of pancreatic stellate cells (PSCs), which are key regulators of fibrosis in vivo. While there is increasing interest in the regulation of PD-...

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Detalles Bibliográficos
Autores principales: Ebine, Kazumi, Kumar, Krishan, Pham, Thao N., Shields, Mario A., Collier, Katharine A., Shang, Meng, DeCant, Brian T., Urrutia, Raul, Hwang, Rosa F., Grimaldo, Sam, Principe, Daniel R., Grippo, Paul J., Bentrem, David J., Munshi, Hidayatullah G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125340/
https://www.ncbi.nlm.nih.gov/pubmed/30185888
http://dx.doi.org/10.1038/s41598-018-31658-1