Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development

The inheritance of gene expression patterns is dependent on epigenetic regulation, but the establishment and maintenance of epigenetic landscapes during T cell differentiation are incompletely understood. Here we show that two stage-specific Cd4 cis-elements, the previously characterized enhancer E4...

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Detalles Bibliográficos
Autores principales: Issuree, Priya D., Day, Kenneth, Au, Christy, Raviram, Ramya, Zappile, Paul, Skok, Jane A., Xue, Hai-Hui, Myers, Richard M., Littman, Dan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125341/
https://www.ncbi.nlm.nih.gov/pubmed/30185805
http://dx.doi.org/10.1038/s41467-018-05834-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125341/
https://www.ncbi.nlm.nih.gov/pubmed/30185805
http://dx.doi.org/10.1038/s41467-018-05834-w

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