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Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development
The inheritance of gene expression patterns is dependent on epigenetic regulation, but the establishment and maintenance of epigenetic landscapes during T cell differentiation are incompletely understood. Here we show that two stage-specific Cd4 cis-elements, the previously characterized enhancer E4...
Autores principales: | Issuree, Priya D., Day, Kenneth, Au, Christy, Raviram, Ramya, Zappile, Paul, Skok, Jane A., Xue, Hai-Hui, Myers, Richard M., Littman, Dan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125341/ https://www.ncbi.nlm.nih.gov/pubmed/30185805 http://dx.doi.org/10.1038/s41467-018-05834-w |
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