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Integrative Profiling of Alternative Splicing Induced by U2AF1 S34F Mutation in Lung Adenocarcinoma Reveals a Mechanistic Link to Mitotic Stress

Mutations in spliceosome components have been implicated in carcinogenesis of various types of cancer. One of the most frequently found is U2AF1 S34F missense mutation. Functional analyses of this mutation have been largely limited to hematological malignancies although the mutation is also frequent...

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Detalles Bibliográficos
Autores principales: Kim, Suyeon, Park, Charny, Jun, Yukyung, Lee, Sanghyuk, Jung, Yeonjoo, Kim, Jaesang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125417/
https://www.ncbi.nlm.nih.gov/pubmed/29991672
http://dx.doi.org/10.14348/molcells.2018.0176