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Abrogation of the Circadian Nuclear Receptor REV-ERBα Exacerbates 6-Hydroxydopamine-Induced Dopaminergic Neurodegeneration

Parkinson’s disease (PD) is a neurodegenerative disease characterized by progressive degeneration of dopaminergic (DAergic) neurons, particularly in the substantia nigra (SN). Although circadian dysfunction has been suggested as one of the pathophysiological risk factors for PD, the exact molecular...

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Detalles Bibliográficos
Autores principales: Kim, Jeongah, Jang, Sangwon, Choi, Mijung, Chung, Sooyoung, Choe, Youngshik, Choe, Han Kyoung, Son, Gi Hoon, Rhee, Kunsoo, Kim, Kyungjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125424/
https://www.ncbi.nlm.nih.gov/pubmed/30078232
http://dx.doi.org/10.14348/molcells.2018.0201