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Changes in plasma membrane damage inducing cell death after treatment with near‐infrared photoimmunotherapy

Near‐infrared photoimmunotherapy (NIR‐PIT) is a new cancer phototherapy modality using an antibody conjugated to a photosensitizer, IRDye700DX. When the conjugate binds to the plasma membrane and is exposed to NIR light, NIR‐PIT‐treated cells undergo swelling, and target‐selective necrotic/immunogen...

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Detalles Bibliográficos
Autores principales: Nakajima, Kohei, Takakura, Hideo, Shimizu, Yoichi, Ogawa, Mikako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125438/
https://www.ncbi.nlm.nih.gov/pubmed/29949672
http://dx.doi.org/10.1111/cas.13713