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UNC119 is a binding partner of tumor suppressor Ras‐association domain family 6 and induces apoptosis and cell cycle arrest by MDM2 and p53

Ras‐association domain family 6 (RASSF6) is a tumor suppressor that interacts with MDM2 and stabilizes p53. Caenorhabditis elegans unc‐119 encodes a protein that is required for normal development of the nervous system. Humans have 2 unc‐119 homologues, UNC119 and UNC119B. We have identified UNC119...

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Detalles Bibliográficos
Autores principales: Iwasa, Hiroaki, Sarkar, Aradhan, Shimizu, Takanobu, Sawada, Takeru, Hossain, Shakhawoat, Xu, Xiaoyin, Maruyama, Junichi, Arimoto‐Matsuzaki, Kyoko, Withanage, Kanchanamala, Nakagawa, Kentaro, Kurihara, Hidetake, Kuroyanagi, Hidehito, Hata, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125449/
https://www.ncbi.nlm.nih.gov/pubmed/29931788
http://dx.doi.org/10.1111/cas.13706