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Inhibition of stromal‐interacting molecule 1‐mediated store‐operated Ca(2+) entry as a novel strategy for the treatment of acquired imatinib‐resistant gastrointestinal stromal tumors

Imatinib has revolutionized the treatment of gastrointestinal stromal tumors (GIST); however, primary and secondary resistance to imatinib is still a major cause of treatment failure. Multiple mechanisms are involved in this progression. In the present study, we reported a novel mechanism for the ac...

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Detalles Bibliográficos
Autores principales: Yang, Ziyi, Pan, Lijia, Liu, Shilei, Li, Fengnan, Lv, Wenjie, Shu, Yijun, Dong, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125455/
https://www.ncbi.nlm.nih.gov/pubmed/29957833
http://dx.doi.org/10.1111/cas.13718