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BH3 mimetics induce apoptosis independent of DRP-1 in melanoma

Despite the recent advancement in treating melanoma, options are still limited for patients without BRAF mutations or in relapse from current treatments. BH3 mimetics against members of the BCL-2 family have gained excitement with the recent success in hematological malignancies. However, single dru...

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Detalles Bibliográficos
Autores principales: Mukherjee, Nabanita, Strosnider, Andrew, Vagher, Bay, Lambert, Karoline A., Slaven, Sarah, Robinson, William A., Amato, Carol M., Couts, Kasey L., Bemis, Judson G. T., Turner, Jacqueline A., Norris, David A., Shellman, Yiqun G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125485/
https://www.ncbi.nlm.nih.gov/pubmed/30185782
http://dx.doi.org/10.1038/s41419-018-0932-z