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In Vitro and In Vivo Characterization of NOSO-502, a Novel Inhibitor of Bacterial Translation

Antibacterial activity screening of a collection of Xenorhabdus strains led to the discovery of the odilorhabdins, a new antibiotic class with broad-spectrum activity against Gram-positive and Gram-negative pathogens. Odilorhabdins inhibit bacterial translation by a new mechanism of action on riboso...

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Detalles Bibliográficos
Autores principales: Racine, Emilie, Nordmann, Patrice, Pantel, Lucile, Sarciaux, Matthieu, Serri, Marine, Houard, Jessica, Villain-Guillot, Philippe, Demords, Anthony, Vingsbo Lundberg, Carina, Gualtieri, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125496/
https://www.ncbi.nlm.nih.gov/pubmed/29987155
http://dx.doi.org/10.1128/AAC.01016-18