CD69 enhances immunosuppressive function of regulatory T-cells and attenuates colitis by prompting IL-10 production

Foxp3(+) regulatory T cells (Tregs) can inhibit immune responses and maintain immune tolerance by secreting immunosuppressive TGF-β1 and IL-10. However, the efficiency of Tregs become the major obstacle to their use for immunotherapy. In this study, we investigated the relevance of the C-type lectin...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Yang, Fei, Zhang, Fanghui, Guo, Danfeng, Li, Ling, Wang, Xian, Liang, Tingbo, Wang, Jianli, Cai, Zhijian, Jin, Hongchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125584/
https://www.ncbi.nlm.nih.gov/pubmed/30185773
http://dx.doi.org/10.1038/s41419-018-0927-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125584/
https://www.ncbi.nlm.nih.gov/pubmed/30185773
http://dx.doi.org/10.1038/s41419-018-0927-9

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