Characterization of Mutations in the Mitochondrial Encoded Electron Transport Chain Complexes in Acute Myeloid Leukemia

Acute Myeloid Leukemia is a devastating and heterogeneous, hematological malignancy characterized by the uncontrolled proliferation of undifferentiated myeloid progenitor cells—blasts. Mutations in certain mitochondrial proteins, such as IDH2 have been shown to contribute to leukemogenesis. However,...

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Detalles Bibliográficos
Autores principales: Wu, Sharon, Akhtari, Mojtaba, Alachkar, Houda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125587/
https://www.ncbi.nlm.nih.gov/pubmed/30185817
http://dx.doi.org/10.1038/s41598-018-31489-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125587/
https://www.ncbi.nlm.nih.gov/pubmed/30185817
http://dx.doi.org/10.1038/s41598-018-31489-0

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