Malignant Transformation of Human Bronchial Epithelial Cells Induced by Arsenic through STAT3/miR-301a/SMAD4 Loop

Arsenic is a well-known of human carcinogen and miR-301a is an oncogenic microRNA, which links to oncogenesis, however, little is understood about its contribution to arsenic-induced cellular transformation and tumorigenesis. Here, we investigated the role of miR-301a during arsenic-induced cellular...

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Detalles Bibliográficos
Autores principales: Zhong, Mingtian, Huang, Zhujuan, Wang, Lei, Lin, Zhanwen, Cao, Zhi, Li, Xun, Zhang, Fengxue, Wang, Hongqi, Li, Yong, Ma, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125593/
https://www.ncbi.nlm.nih.gov/pubmed/30185897
http://dx.doi.org/10.1038/s41598-018-31516-0