Cargando…
Malignant Transformation of Human Bronchial Epithelial Cells Induced by Arsenic through STAT3/miR-301a/SMAD4 Loop
Arsenic is a well-known of human carcinogen and miR-301a is an oncogenic microRNA, which links to oncogenesis, however, little is understood about its contribution to arsenic-induced cellular transformation and tumorigenesis. Here, we investigated the role of miR-301a during arsenic-induced cellular...
Autores principales: | Zhong, Mingtian, Huang, Zhujuan, Wang, Lei, Lin, Zhanwen, Cao, Zhi, Li, Xun, Zhang, Fengxue, Wang, Hongqi, Li, Yong, Ma, Xiaodong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125593/ https://www.ncbi.nlm.nih.gov/pubmed/30185897 http://dx.doi.org/10.1038/s41598-018-31516-0 |
Ejemplares similares
-
miR-301a promotes lung tumorigenesis by suppressing Runx3
por: Li, Xun, et al.
Publicado: (2019) -
Arsenic activates STAT3 signaling during the transformation of the human bronchial epithelial cells
por: Almutairy, Bandar, et al.
Publicado: (2022) -
Inflammatory-miR-301a circuitry drives mTOR and Stat3-dependent PSC activation in chronic pancreatitis and PanIN
por: Li, Fugui, et al.
Publicado: (2022) -
Metabolomic dynamics of the arsenic-transformed bronchial epithelial cells and the derived cancer stem-like cells
por: Fu, Yao, et al.
Publicado: (2022) -
Akt Activation Is Responsible for Enhanced Migratory and Invasive Behavior of Arsenic-Transformed Human Bronchial Epithelial Cells
por: Wang, Zhishan, et al.
Publicado: (2011)