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Time-lapse imaging of molecular evolution by high-throughput sequencing

High-throughput sequencing of in vitro selection could artificially provide large quantities of relic sequences from known times of molecular evolution. Here, we demonstrate how it can be used to reconstruct an empirical genealogical evolutionary (EGE) tree of an aptamer family. In contrast to class...

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Detalles Bibliográficos
Autores principales: Nguyen Quang, Nam, Bouvier, Clément, Henriques, Adrien, Lelandais, Benoit, Ducongé, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125620/
https://www.ncbi.nlm.nih.gov/pubmed/29982617
http://dx.doi.org/10.1093/nar/gky583