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Trypanosoma brucei UMSBP2 is a single-stranded telomeric DNA binding protein essential for chromosome end protection

Universal minicircle sequence binding proteins (UMSBPs) are CCHC-type zinc-finger proteins that bind a single-stranded G-rich sequence, UMS, conserved at the replication origins of the mitochondrial (kinetoplast) DNA of trypanosomatids. Here, we report that Trypanosoma brucei TbUMSBP2, which has bee...

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Detalles Bibliográficos
Autores principales: Klebanov-Akopyan, Olga, Mishra, Amartya, Glousker, Galina, Tzfati, Yehuda, Shlomai, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125633/
https://www.ncbi.nlm.nih.gov/pubmed/30007364
http://dx.doi.org/10.1093/nar/gky597