Dynamics of supercoiled DNA with complex knots: large-scale rearrangements and persistent multi-strand interlocking

Knots and supercoiling are both introduced in bacterial plasmids by catalytic processes involving DNA strand passages. While the effects on plasmid organization has been extensively studied for knotting and supercoiling taken separately, much less is known about their concurrent action. Here, we use...

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Detalles Bibliográficos
Autores principales: Coronel, Lucia, Suma, Antonio, Micheletti, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125635/
https://www.ncbi.nlm.nih.gov/pubmed/29931074
http://dx.doi.org/10.1093/nar/gky523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125635/
https://www.ncbi.nlm.nih.gov/pubmed/29931074
http://dx.doi.org/10.1093/nar/gky523

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