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Chromosomal over-replication in Escherichia coli recG cells is triggered by replication fork fusion and amplified if replichore symmetry is disturbed

Chromosome duplication initiates via the assembly of replication forks at defined origins. Forks proceed in opposite directions until they fuse with a converging fork. Recent work highlights that fork fusions are highly choreographed both in pro- and eukaryotic cells. The circular Escherichia coli c...

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Detalles Bibliográficos
Autores principales: Midgley-Smith, Sarah L, Dimude, Juachi U, Taylor, Toni, Forrester, Nicole M, Upton, Amy L, Lloyd, Robert G, Rudolph, Christian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125675/
https://www.ncbi.nlm.nih.gov/pubmed/29982635
http://dx.doi.org/10.1093/nar/gky566