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Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity

The nuclear pore complex (NPC) machinery is emerging as an important determinant in the maintenance of genome integrity and sensitivity to DNA double-strand break (DSB)-inducing agents, such as ionising radiation (IR). In this study, using a high-throughput siRNA screen, we identified the central ch...

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Detalles Bibliográficos
Autores principales: Rodriguez-Berriguete, Gonzalo, Granata, Giovanna, Puliyadi, Rathi, Tiwana, Gaganpreet, Prevo, Remko, Wilson, Rhodri S, Yu, Sheng, Buffa, Francesca, Humphrey, Timothy C, McKenna, W Gillies, Higgins, Geoff S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125679/
https://www.ncbi.nlm.nih.gov/pubmed/29986057
http://dx.doi.org/10.1093/nar/gky569