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Synthetic switch-based baculovirus for transgene expression control and selective killing of hepatocellular carcinoma cells
Baculovirus (BV) holds promise as a vector for anticancer gene delivery to combat the most common liver cancer–hepatocellular carcinoma (HCC). However, in vivo BV administration inevitably results in BV entry into non-HCC normal cells, leaky anticancer gene expression and possible toxicity. To impro...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125686/ https://www.ncbi.nlm.nih.gov/pubmed/29905834 http://dx.doi.org/10.1093/nar/gky447 |