Cargando…

Synthetic switch-based baculovirus for transgene expression control and selective killing of hepatocellular carcinoma cells

Baculovirus (BV) holds promise as a vector for anticancer gene delivery to combat the most common liver cancer–hepatocellular carcinoma (HCC). However, in vivo BV administration inevitably results in BV entry into non-HCC normal cells, leaky anticancer gene expression and possible toxicity. To impro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Mei-Wei, Tseng, Yen-Wen, Shen, Chih-Che, Hsu, Mu-Nung, Hwu, Jih-Ru, Chang, Chin-Wei, Yeh, Chung-Ju, Chou, Min-Yuan, Wu, Jaw-Ching, Hu, Yu-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125686/ https://www.ncbi.nlm.nih.gov/pubmed/29905834 http://dx.doi.org/10.1093/nar/gky447

Ejemplares similares

Synthetic switch to minimize CRISPR off-target effects by self-restricting Cas9 transcription and translation
por: Shen, Chih-Che, et al.
Publicado: (2019)

Enhanced and prolonged baculovirus-mediated expression by incorporating recombinase system and in cis elements: a comparative study
por: Sung, Li-Yu, et al.
Publicado: (2013)

CRISPRai for simultaneous gene activation and inhibition to promote stem cell chondrogenesis and calvarial bone regeneration
por: Truong, Vu Anh, et al.
Publicado: (2019)

Synthetic circular RNA switches and circuits that control protein expression in mammalian cells
por: Kameda, Shigetoshi, et al.
Publicado: (2023)

Counter-selection recombineering of the baculovirus genome: a strategy for seamless modification of repeat-containing BACs
por: Westenberg, Marcel, et al.
Publicado: (2010)

Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals
por: Atanasov, Janina, et al.
Publicado: (2017)

Transgenic zebrafish model to study translational control mediated by upstream open reading frame of human chop gene
por: Lee, Hung-Chieh, et al.
Publicado: (2011)

Efficient mapping of transgene integration sites and local structural changes in Cre transgenic mice using targeted locus amplification
por: Cain-Hom, Carol, et al.
Publicado: (2017)

Manipulating transgenes using a chromosome vector
por: Ikeno, Masashi, et al.
Publicado: (2009)

Broad-host-range vector system for synthetic biology and biotechnology in cyanobacteria
por: Taton, Arnaud, et al.
Publicado: (2014)

Vitamin H-regulated transgene expression in mammalian cells
por: Weber, Wilfried, et al.
Publicado: (2007)

Toxin–antitoxin based transgene expression in mammalian cells
por: Nehlsen, K., et al.
Publicado: (2010)

PiggyBac transgenic strategies in the developing chicken spinal cord
por: Lu, Yanyan, et al.
Publicado: (2009)

Cosmetics-triggered percutaneous remote control of transgene expression in mice
por: Wang, Hui, et al.
Publicado: (2015)

A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts
por: Zheng, Yang, et al.
Publicado: (2019)

The synthetic integron: an in vivo genetic shuffling device
por: Bikard, David, et al.
Publicado: (2010)

Engineering of synthetic, stress-responsive yeast promoters
por: Rajkumar, Arun S., et al.
Publicado: (2016)

Direct optical mapping of transcription factor binding sites on field-stretched λ-DNA in nanofluidic devices
por: Sriram, K. K., et al.
Publicado: (2014)

High-level transgene expression by homologous recombination-mediated gene transfer
por: Grandjean, Mélanie, et al.
Publicado: (2011)

Correcting errors in synthetic DNA through consensus shuffling
por: Binkowski, Brock F., et al.
Publicado: (2005)

A synthetic mammalian electro-genetic transcription circuit
por: Weber, Wilfried, et al.
Publicado: (2009)

Site-specific chromosomal integration of large synthetic constructs
por: Kuhlman, Thomas E., et al.
Publicado: (2010)

Sequence verification of synthetic DNA by assembly of sequencing reads
por: Wilson, Mandy L., et al.
Publicado: (2013)

Synthetic mammalian trigger-controlled bipartite transcription factors
por: Folcher, Marc, et al.
Publicado: (2013)

A synthetic RNA-mediated evolution system in yeast
por: Jensen, Emil D, et al.
Publicado: (2021)

CREEPY: CRISPR-mediated editing of synthetic episomes in yeast
por: Zhao, Yu, et al.
Publicado: (2023)

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation
por: Kaufman, Weimin L., et al.
Publicado: (2008)

Efficient integration of transgenes into a defined locus in human embryonic stem cells
por: Sakurai, Kenji, et al.
Publicado: (2010)

The food additive vanillic acid controls transgene expression in mammalian cells and mice
por: Gitzinger, Marc, et al.
Publicado: (2012)

Baculoviral transduction facilitates TALEN-mediated targeted transgene integration and Cre/LoxP cassette exchange in human-induced pluripotent stem cells
por: Zhu, Haibao, et al.
Publicado: (2013)

Systematic screens of proteins binding to synthetic microRNA precursors
por: Towbin, Harry, et al.
Publicado: (2013)

New synthetic substrates of mammalian nucleotide excision repair system
por: Evdokimov, Alexey, et al.
Publicado: (2013)

ROS-DET: robust detector of switching mechanisms in gene expression
por: Kayano, Mitsunori, et al.
Publicado: (2011)

Pronuclear injection-based mouse targeted transgenesis for reproducible and highly efficient transgene expression
por: Ohtsuka, Masato, et al.
Publicado: (2010)

Use of microarray hybrid capture and next-generation sequencing to identify the anatomy of a transgene
por: DuBose, Amanda J., et al.
Publicado: (2013)

Removal of mismatched bases from synthetic genes by enzymatic mismatch cleavage
por: Fuhrmann, Markus, et al.
Publicado: (2005)

Genome engineering using a synthetic gene circuit in Bacillus subtilis
por: Jeong, Da-Eun, et al.
Publicado: (2015)

Metabolic tinker: an online tool for guiding the design of synthetic metabolic pathways
por: McClymont, Kent, et al.
Publicado: (2013)

Cre reconstitution allows for DNA recombination selectively in dual-marker-expressing cells in transgenic mice
por: Xu, Yanwen, et al.
Publicado: (2007)

Rational design of a small molecule-responsive intramer controlling transgene expression in mammalian cells
por: Ausländer, David, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_jjotd10dd6hththnfveo4q7dlo