Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide

The next challenge in synthetic biology is to be able to replicate synthetic nucleic acid sequences efficiently. The synthetic pair, 2-amino-8-(1-beta-d-2′- deoxyribofuranosyl) imidazo [1,2-a]-1,3,5-triazin-[8H]-4-one (trivially designated P) with 6-amino-3-(2′-deoxyribofuranosyl)-5-nitro-1H-pyridin...

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Detalles Bibliográficos
Autores principales: Singh, Isha, Laos, Roberto, Hoshika, Shuichi, Benner, Steven A, Georgiadis, Millie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125688/
https://www.ncbi.nlm.nih.gov/pubmed/29986111
http://dx.doi.org/10.1093/nar/gky552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125688/
https://www.ncbi.nlm.nih.gov/pubmed/29986111
http://dx.doi.org/10.1093/nar/gky552

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