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Extensive host immune adaptation in a concentrated North American HIV epidemic

OBJECTIVE: HIV incidence in the Canadian province of Saskatchewan, where Indigenous persons make up 80% of those infected, are among the highest on the continent. Reports of accelerated HIV progression, associated with carriage of certain human leukocyte antigen (HLA) alleles (including the typicall...

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Detalles Bibliográficos
Autores principales: Brumme, Zabrina L., Kinloch, Natalie N., Sanche, Stephen, Wong, Alexander, Martin, Eric, Cobarrubias, Kyle D., Sandstrom, Paul, Levett, Paul N., Harrigan, P. Richard, Joy, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125742/
https://www.ncbi.nlm.nih.gov/pubmed/30048246
http://dx.doi.org/10.1097/QAD.0000000000001912