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Gata4-Dependent Differentiation of c-Kit(+)–Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart
BACKGROUND: Although c-Kit(+) adult progenitor cells were initially reported to produce new cardiomyocytes in the heart, recent genetic evidence suggests that such events are exceedingly rare. However, to determine if these rare events represent true de novo cardiomyocyte formation, we deleted the n...
Autores principales: | Maliken, Bryan D., Kanisicak, Onur, Karch, Jason, Khalil, Hadi, Fu, Xing, Boyer, Justin G., Prasad, Vikram, Zheng, Yi, Molkentin, Jeffery D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125755/ https://www.ncbi.nlm.nih.gov/pubmed/29666070 http://dx.doi.org/10.1161/CIRCULATIONAHA.118.033703 |
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