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The putative tumour suppressor miR-1-3p modulates prostate cancer cell aggressiveness by repressing E2F5 and PFTK1

BACKGROUND: Previous studies report that miR-1-3p, a member of the microRNA-1 family (miR-1), and functions as a tumor suppressor in several different cancers. However, little is known regarding the biological role and intrinsic regulatory mechanisms of miR-1-3p in prostate cancer (PCa). METHODS: In...

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Detalles Bibliográficos
Autores principales: Li, Sen-Mao, Wu, Huan-Lei, Yu, Xiao, Tang, Kun, Wang, Shao-Gang, Ye, Zhang-Qun, Hu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125869/
https://www.ncbi.nlm.nih.gov/pubmed/30185212
http://dx.doi.org/10.1186/s13046-018-0895-z