ERRα suppression enhances the cytotoxicity of the MEK inhibitor trametinib against colon cancer cells

BACKGROUND: ERRα, a constitutive transcription factor that regulates energy metabolism, plays an important role in the progression of various tumours. However, its role in cell survival and proliferation and its implication in targeted therapy in colon cancer remains elusive. METHODS: The expression...

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Detalles Bibliográficos
Autores principales: Zhou, Sheng, Xia, Hongwei, Xu, Huanji, Tang, Qiulin, Nie, Yongzhan, Gong, Qi yong, Bi, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125878/
https://www.ncbi.nlm.nih.gov/pubmed/30185207
http://dx.doi.org/10.1186/s13046-018-0862-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125878/
https://www.ncbi.nlm.nih.gov/pubmed/30185207
http://dx.doi.org/10.1186/s13046-018-0862-8

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