Evaluation of anti-PD-1-based therapy against triple-negative breast cancer patient-derived xenograft tumors engrafted in humanized mouse models

BACKGROUND: Breast cancer has been considered not highly immunogenic, and few patients benefit from current immunotherapies. However, new strategies are aimed at changing this paradigm. In the present study, we examined the in vivo activity of a humanized anti-programmed cell death protein 1 (anti-P...

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Detalles Bibliográficos
Autores principales: Rosato, Roberto R., Dávila-González, Daniel, Choi, Dong Soon, Qian, Wei, Chen, Wen, Kozielski, Anthony J., Wong, Helen, Dave, Bhuvanesh, Chang, Jenny C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125882/
https://www.ncbi.nlm.nih.gov/pubmed/30185216
http://dx.doi.org/10.1186/s13058-018-1037-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125882/
https://www.ncbi.nlm.nih.gov/pubmed/30185216
http://dx.doi.org/10.1186/s13058-018-1037-4

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