A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer

BACKGROUND: This phase Ib study (NCT00960960) evaluated pictilisib (GDC-0941; pan-phosphatidylinositol 3-kinase inhibitor) plus paclitaxel, with and without bevacizumab or trastuzumab, or in combination with letrozole, in patients with locally recurrent or metastatic breast cancer. METHODS: This was...

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Detalles Bibliográficos
Autores principales: Schöffski, Patrick, Cresta, Sara, Mayer, Ingrid A., Wildiers, Hans, Damian, Silvia, Gendreau, Steven, Rooney, Isabelle, Morrissey, Kari M., Spoerke, Jill M., Ng, Vivian W., Singel, Stina M., Winer, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125885/
https://www.ncbi.nlm.nih.gov/pubmed/30185228
http://dx.doi.org/10.1186/s13058-018-1015-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125885/
https://www.ncbi.nlm.nih.gov/pubmed/30185228
http://dx.doi.org/10.1186/s13058-018-1015-x

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