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Ginsenoside Rb1 administration attenuates focal cerebral ischemic reperfusion injury through inhibition of HMGB1 and inflammation signals

High-mobility group box 1 (HMGB1) is released after focal cerebral ischemia/reperfusion (I/R), and aggravates brain tissue damage. Ginsenoside Rb1 (Rb1), isolated from Panax ginseng, has been reported to inhibit I/R-induced cell death in the brain. The present study aimed to investigate the protecti...

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Detalles Bibliográficos
Autores principales: Liu, Anxin, Zhu, Weiwei, Sun, Lirui, Han, Guangming, Liu, Huiping, Chen, Zhaoyu, Zhuang, Li, Jiang, Wen, Xue, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125983/
https://www.ncbi.nlm.nih.gov/pubmed/30214520
http://dx.doi.org/10.3892/etm.2018.6523