Cargando…

Ginsenoside Rb1 administration attenuates focal cerebral ischemic reperfusion injury through inhibition of HMGB1 and inflammation signals

High-mobility group box 1 (HMGB1) is released after focal cerebral ischemia/reperfusion (I/R), and aggravates brain tissue damage. Ginsenoside Rb1 (Rb1), isolated from Panax ginseng, has been reported to inhibit I/R-induced cell death in the brain. The present study aimed to investigate the protecti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Anxin, Zhu, Weiwei, Sun, Lirui, Han, Guangming, Liu, Huiping, Chen, Zhaoyu, Zhuang, Li, Jiang, Wen, Xue, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125983/ https://www.ncbi.nlm.nih.gov/pubmed/30214520 http://dx.doi.org/10.3892/etm.2018.6523

Ejemplares similares

Effects of ginsenoside Rb1 on spinal cord ischemia-reperfusion injury in rats
por: Ye, Jin-tao, et al.
Publicado: (2019)

Ginsenoside Rb1 for Myocardial Ischemia/Reperfusion Injury: Preclinical Evidence and Possible Mechanisms
por: Zheng, Qun, et al.
Publicado: (2017)

Ginsenoside Rb1 Attenuates Intestinal Ischemia Reperfusion Induced Renal Injury by Activating Nrf2/ARE Pathway
por: Sun, Qian, et al.
Publicado: (2012)

Antiobesity and Antihyperglycemic Effects of Ginsenoside Rb1 in Rats
por: Xiong, Ye, et al.
Publicado: (2010)

Ginsenoside-Rb1 Protects Hypoxic- and Ischemic-Damaged Cardiomyocytes by Regulating Expression of miRNAs
por: Yan, Xu, et al.
Publicado: (2015)

Combination of the ginsenosides Rb3 and Rb2 exerts protective effects against myocardial ischemia reperfusion injury in rats
por: Liu, Xiaomin, et al.
Publicado: (2020)

Effects of Ginsenoside Rb(1) on Skin Changes
por: Kimura, Yoshiyuki, et al.
Publicado: (2012)

Ginsenoside Rb1 Preconditioning Enhances eNOS Expression and Attenuates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats
por: Xia, Rui, et al.
Publicado: (2011)

Protective Effect of Ginsenoside Rb1 against Intestinal Ischemia-Reperfusion Induced Acute Renal Injury in Mice
por: Sun, Qian, et al.
Publicado: (2013)

Combined Use of Emodin and Ginsenoside Rb1 Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Rats
por: Li, Yan, et al.
Publicado: (2018)

Protective Effect of Ginsenoside Rb1 Against Lung Injury Induced by Intestinal Ischemia-Reperfusion in Rats
por: Wang, Jin, et al.
Publicado: (2013)

Progress in the Conversion of Ginsenoside Rb1 into Minor Ginsenosides Using β-Glucosidases
por: Zhu, Hongrong, et al.
Publicado: (2023)

Ginsenoside Rb1 attenuates diabetic retinopathy in streptozotocin-induced diabetic rats
por: Dong, Changxia, et al.
Publicado: (2019)

Ginsenoside Rb1 attenuates activated microglia-induced neuronal damage
por: Ke, Lining, et al.
Publicado: (2014)

Metabolism Study of Notoginsenoside R(1), Ginsenoside Rg(1) and Ginsenoside Rb(1) of Radix Panax Notoginseng in Zebrafish
por: Wei, Yingjie, et al.
Publicado: (2011)

Myostain is involved in ginsenoside Rb1-mediated anti-obesity
por: Li, Hong-Shi, et al.
Publicado: (2022)

Ginsenoside Rb1 inhibits astrocyte activation and promotes transfer of astrocytic mitochondria to neurons against ischemic stroke
por: Ni, Xue-Chun, et al.
Publicado: (2022)

Synthesis of ginsenoside Rb(1)-imprinted magnetic polymer nanoparticles for the extraction and cellular delivery of therapeutic ginsenosides
por: Liu, Kai-Hsi, et al.
Publicado: (2022)

Ginsenoside-Rb3 protects the myocardium from ischemia-reperfusion injury via the inhibition of apoptosis in rats
por: LIU, XIAOMIN, et al.
Publicado: (2014)

Attenuating effect of Ginsenoside Rb1 on LPS-induced lung injury in rats
por: Yuan, Qing, et al.
Publicado: (2014)

Ginsenoside Rb1 Treatment Attenuates Pulmonary Inflammatory Cytokine Release and Tissue Injury following Intestinal Ischemia Reperfusion Injury in Mice
por: Jiang, Ying, et al.
Publicado: (2015)

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1
por: Vo, Hoang Tung, et al.
Publicado: (2015)

Translational potential of ginsenoside Rb1 in managing progression of osteoarthritis
por: Chen, Yuanfeng, et al.
Publicado: (2016)

Comprehensive multiomics analysis of the effect of ginsenoside Rb1 on hyperlipidemia
por: Lianqun, Jia, et al.
Publicado: (2021)

Molecular-Signaling Pathways of Ginsenosides Rb in Myocardial Ischemia-Reperfusion Injury: A Mini Review
por: Ramli, Fitri Fareez, et al.
Publicado: (2022)

Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I
por: Jiang, Lujing, et al.
Publicado: (2021)

Ginsenoside Rb1 attenuates age-associated vascular impairment by modulating the Gas6 pathway
por: Ke, Shiye, et al.
Publicado: (2021)

Ginsenoside-Rb1 for Ischemic Stroke: A Systematic Review and Meta-analysis of Preclinical Evidence and Possible Mechanisms
por: Shi, Yi-Hua, et al.
Publicado: (2020)

Brain Transport Profiles of Ginsenoside Rb(1) by Glucose Transporter 1: In Vitro and in Vivo
por: Wang, Yu-Zhu, et al.
Publicado: (2018)

Neuroprotective effects of ginsenoside Rb1 on hippocampal neuronal injury and neurite outgrowth
por: Liu, Juan, et al.
Publicado: (2014)

Design of an Anti-HMGB1 Synthetic Antibody for In Vivo Ischemic/Reperfusion Injury Therapy
por: Koide, Hiroyuki, et al.
Publicado: (2023)

Ginsenoside Rb1 Ameliorates Diabetic Arterial Stiffening via AMPK Pathway
por: Zhang, Xinyu, et al.
Publicado: (2021)

Ginsenoside Rb1 Reduces Isoproterenol-Induced Cardiomyocytes Apoptosis In Vitro and In Vivo
por: Wang, Xiu-feng, et al.
Publicado: (2013)

Ginsenoside Rb1 improves cardiac function and remodeling in heart failure
por: Zheng, Xian, et al.
Publicado: (2017)

Ginsenoside Rb1 ameliorates cisplatin-induced learning and memory impairments
por: Chen, Chen, et al.
Publicado: (2019)

Neuroprotective Mechanisms of Ginsenoside Rb1 in Central Nervous System Diseases
por: Gong, Liang, et al.
Publicado: (2022)

Tolerability and pharmacokinetics of ginsenosides Rb1, Rb2, Rc, Rd, and compound K after single or multiple administration of red ginseng extract in human beings
por: Choi, Min-Koo, et al.
Publicado: (2020)

Ginsenoside Rb1 attenuates intestinal ischemia/reperfusion-induced inflammation and oxidative stress via activation of the PI3K/Akt/Nrf2 signaling pathway
por: Chen, Sufang, et al.
Publicado: (2019)

Pharmacokinetics of ginsenoside Rb1 and its metabolite compound K after oral administration of Korean Red Ginseng extract
por: Kim, Hyung-Ki
Publicado: (2013)

Ginsenoside Rb1 regulates prefrontal cortical GABAergic transmission in MPTP-treated mice
por: Liu, Yan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jpbjtvb689anolggtbp07qsk6e