Proanthocyanidin B2 attenuates high-glucose-induced neurotoxicity of dorsal root ganglion neurons through the PI3K/Akt signaling pathway

High glucose affects primary afferent neurons in dorsal root ganglia by inhibiting neurite elongation, causing oxidative stress, and inducing neuronal apoptosis and mitochondrial dysfunction, which finally result in neuronal damage. Proanthocyanidin, a potent antioxidant, has been shown to have neur...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan-Pin, Liu, Si-Yan, Sun, Qian-Yu, Ren, Jing, Liu, Hua-Xiang, Li, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126122/
https://www.ncbi.nlm.nih.gov/pubmed/30127125
http://dx.doi.org/10.4103/1673-5374.237174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126122/
https://www.ncbi.nlm.nih.gov/pubmed/30127125
http://dx.doi.org/10.4103/1673-5374.237174

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