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Activated complement protein C5a does not affect brain-derived endothelial cell viability and zonula occludens-1 levels following oxygen-glucose deprivation

BACKGROUND AND PURPOSE: Ischemic brain injury induces both functional and structural disarray affecting the blood–brain barrier (BBB) which in return aggravates stroke outcomes. Complement system and its bioactive proteins are important molecular responders to ischemia. C5a protein along with its re...

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Detalles Bibliográficos
Autores principales: Khoyetsyan, Aren, Kacimi, Rachid, Tsakanova, Gohar, Boyajyan, Anna, Arakelyan, Arsen, Yenari, Midori A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126234/
https://www.ncbi.nlm.nih.gov/pubmed/30276299
http://dx.doi.org/10.4103/2394-8108.203258