Proteomic Analysis of Hippocampus in a Mouse Model of Depression Reveals Neuroprotective Function of Ubiquitin C-terminal Hydrolase L1 (UCH-L1) via Stress-induced Cysteine Oxidative Modifications

Chronic physical restraint stress increases oxidative stress in the brain, and dysregulation of oxidative stress can be one of the causes of major depressive disorder. To understand the underlying mechanisms, we undertook a systematic proteomic analysis of hippocampus in a chronic restraint stress m...

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Detalles Bibliográficos
Autores principales: Choi, Jung-Eun, Lee, Jae-Jin, Kang, Wonmo, Kim, Hyun Jung, Cho, Jin-Hwan, Han, Pyung-Lim, Lee, Kong-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126396/
https://www.ncbi.nlm.nih.gov/pubmed/29959188
http://dx.doi.org/10.1074/mcp.RA118.000835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126396/
https://www.ncbi.nlm.nih.gov/pubmed/29959188
http://dx.doi.org/10.1074/mcp.RA118.000835

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